Shirshendu Mukhopadhyay (Bengali: শীর্ষেন্দু মুখোপাধ্যায়) (born 2 November 1935) is a famous writer in Bengali language. His stories for younger readers are as famous as those aimed at adults.

Shirshendu Mukhopadhyay was born in Bikrampur ( currently in Munshiganj District), now in Bangladesh. He spent his childhood in Bihar and many places in Bengal and Assam accompanying his father, who worked in the railways. He passed intermediate from the Victoria College, Calcutta before taking a Masters in Bengali from the Calcutta University.

Shirshendu started his career as a school teacher and is now on the staff of the Ananda Bazar Patrika at Kolkata. He is associated with a Bengali magazine called Desh.